Dosing Information

injecting

Subcutaneous anti-TNF therapy

Choose an option below to see the recommended CIMZIA dosing schedule for the prefilled syringe or the lyophilized powder for reconstitution.

The dosing schedule is the same for both prefilled syringe for self-administration and lyophilized powder for reconstitution and administration by a healthcare professional.1

RA Loading Dose*

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
0

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
2

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
4

calendar

Initial dosing covers the first month of injections, which are provided at the start of therapy at Week 0, Week 2, and Week 4. Each of these doses is 400 mg, given subcutaneously as 2 separate injections of 200 mg each.

RA Maintenance Dose*

1 INJECTION

200 mg
(200 mg/mL)

Every 2 Weeks
OR

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Every 4 Weeks
 

After initial dosing phase is complete for your RA patient, there are 2 maintenance dosing options available: One 200 mg injection taken every 2 weeks or two 200 mg injections taken every 4 weeks. CIMZIA can be prescribed as monotherapy or in combination with methotrexate.1

PsA Loading Dose*

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
0

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
2

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
4

calendar

Initial dosing covers the first month of injections, which are provided at the start of therapy at Week 0, Week 2, and Week 4. Each of these doses is 400 mg, given subcutaneously as 2 separate injections of 200 mg each.

PsA Maintenance Dose*

1 INJECTION

200 mg
(200 mg/mL)

Every 2 Weeks
OR

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Every 4 Weeks
 

After initial dosing phase is complete for your PsA patient, there are 2 maintenance dosing options available: One 200 mg injection taken every 2 weeks or two 200 mg injections taken every 4 weeks. CIMZIA can be prescribed as monotherapy or in combination with methotrexate.1

AS Loading Dose*

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
0

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
2

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
4

calendar

Initial dosing covers the first month of injections, which are provided at the start of therapy at Week 0, Week 2, and Week 4. Each of these doses is 400 mg, given subcutaneously as 2 separate injections of 200 mg each.

AS Maintenance Dose*

1 INJECTION

200 mg
(200 mg/mL)

Every 2 Weeks
OR

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Every 4 Weeks
 

After initial dosing phase is complete for your AS patient, there are 2 maintenance dosing options available: One 200 mg injection taken every 2 weeks or two 200 mg injections taken every 4 weeks. CIMZIA can be prescribed as monotherapy or in combination with methotrexate.1

CD Loading Dose*

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
0

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
2

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
4

calendar

Initial dosing covers the first month of injections, which are provided at the start of therapy at Week 0, Week 2, and Week 4. Each of these doses is 400 mg, given subcutaneously as 2 separate injections of 200 mg each.

CD Maintenance Dose*

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Every 4 Weeks
 
 
 

After initial dosing phase is complete, for patients who obtain clinical response, the maintenance dose is 400 mg, given as 2 separate injections under the skin of 200 mg (taken every 4 weeks).

PSO Recommended Dose*

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Every 2 Weeks
calendar
 
 

For some patients (with body weight ≤90 kg), the following dose can be considered:

PSO Loading Dose*

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
0

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
2

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
4

calendar

PSO Maintenance Dose*

1 INJECTION

200 mg
(200 mg/mL)

Every 2 Weeks
 
 
 

The recommended dose of CIMZIA for PSO is 400 mg (given as 2 subcutaneous injections of 200 mg each) every other week. For some patients (with body weight ≤90 kg), a dose of 400 mg (given as 2 subcutaneous injections of 200 mg each) initially and at Weeks 2 and 4, followed by 200 mg every other week can be considered.

Nr-axSpA Loading Dose*

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
0

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
2

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Week
4

calendar

Initial dosing covers the first month of injections, which are provided at the start of therapy at Week 0, Week 2, and Week 4. Each of these doses is 400 mg, given subcutaneously as 2 separate injections of 200 mg each.

Nr-axSpA Maintenance Dose*

1 INJECTION

200 mg
(200 mg/mL)

Every 2 Weeks
OR

2 INJECTIONS

400 mg
(200 mg/mL x 2)

Every 4 Weeks
 

After initial dosing phase is complete for your nr-axSpA patient, there are 2 maintenance dosing options available: One 200 mg injection taken every 2 weeks or two 200 mg injections taken every 4 weeks. CIMZIA can be prescribed as monotherapy or in combination with methotrexate.1

* Please see Section 2 of full Prescribing Information for additional dosing and administration information.

Anaphylaxis or serious allergic reactions may occur. Some of these reactions occurred after the first administration of CIMZIA. Hypersensitivity reactions have been reported rarely following CIMZIA administration. The needle shield inside the removable cap of the CIMZIA prefilled syringe contains a derivative of natural rubber latex which may cause an allergic reaction in individuals sensitive to latex.

Prefilled syringe designed for comfort and control in partnership with OXO Good Grips®. Prefilled syringe designed for comfort and control in partnership with OXO Good Grips®.

OXO, Good Grips® and the associated logos are registered trademarks of Helen of Troy Limited and are used under license.